Lee Bermejo's career began in 1997 as an intern at WildStorm. He is self-taught, with little formal art training. His first credited comics work appeared in Gen 13 #43 (Sept. 1999).
His notable works include "What's So Funny About Truth, Justice & the American Way?" story in Action Comics #775, the Lex Luthor: Man of Steel limited series in 2005, the Joker graphic novel, the Batman: Noël graphic novel, Before Watchmen: Rorschach limited series, Suiciders, We Are Robin and Batman Damned.